• Blueprint Medicines average pre-tax profit margin for 2023 was -245.83%, a 12.54% decline from 2022.
• Blueprint Medicines average pre-tax profit margin for 2022 was -281.07%, a 70.92% decline from 2021.
• Blueprint Medicines average pre-tax profit margin for 2021 was -164.45%, a 31.46% increase from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.