• Amgen average pre-tax profit margin for 2023 was 31.43%, a 9.63% decline from 2022.
• Amgen average pre-tax profit margin for 2022 was 28.67%, a 13.19% increase from 2021.
• Amgen average pre-tax profit margin for 2021 was 25.33%, a 22.68% increase from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.