• Amgen average pre-tax profit margin for 2023 was 32.47%, a 17.6% decline from 2022.
• Amgen average pre-tax profit margin for 2022 was 27.61%, a 2.26% increase from 2021.
• Amgen average pre-tax profit margin for 2021 was 27%, a 20.63% increase from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.