• Amgen average gross margin for 2023 was 73.18%, a 3.2% decline from 2022.
• Amgen average gross margin for 2022 was 75.6%, a 0.28% decline from 2021.
• Amgen average gross margin for 2021 was 75.39%, a 2.92% increase from 2020.

Gross margin can be defined as a company's total sales revenue minus its cost of goods sold, divided by the total sales revenue, expressed as a percentage.