• Exelixis average pre-tax profit margin for 2023 was 11.27%, a 47.16% increase from 2022.
• Exelixis average pre-tax profit margin for 2022 was 21.33%, a 60.14% decline from 2021.
• Exelixis average pre-tax profit margin for 2021 was 13.32%, a 49.49% increase from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.