• Exact Sciences average pre-tax profit margin for 2023 was -11.38%, a 67.03% increase from 2022.
• Exact Sciences average pre-tax profit margin for 2022 was -34.52%, a 37.67% decline from 2021.
• Exact Sciences average pre-tax profit margin for 2021 was -55.38%, a 10.06% decline from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.