• Exact Sciences average pre-tax profit margin for 2023 was -15.58%, a 57.26% decline from 2022.
• Exact Sciences average pre-tax profit margin for 2022 was -36.45%, a 37.05% decline from 2021.
• Exact Sciences average pre-tax profit margin for 2021 was -57.9%, a 20.93% decline from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.