• Alnylam Pharmaceuticals average pre-tax profit margin for 2023 was -57.79%, a 47.83% decline from 2022.
• Alnylam Pharmaceuticals average pre-tax profit margin for 2022 was -110.78%, a 10.04% decline from 2021.
• Alnylam Pharmaceuticals average pre-tax profit margin for 2021 was -123.14%, a 48.19% decline from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.