• Insmed average pre-tax profit margin for 2023 was -243.04%, a 24.32% increase from 2022.
• Insmed average pre-tax profit margin for 2022 was -195.49%, a 11.82% increase from 2021.
• Insmed average pre-tax profit margin for 2021 was -221.7%, a 40.62% decline from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.