• Illumina average pre-tax profit margin for 2023 was -60.49%, a 48.59% decline from 2022.
• Illumina average pre-tax profit margin for 2022 was -40.71%, a 277.15% increase from 2021.
• Illumina average pre-tax profit margin for 2021 was 22.98%, a 15.05% decline from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.