• Blueprint Medicines average gross margin for 2023 was 91.38%, a 6.34% increase from 2022.
• Blueprint Medicines average gross margin for 2022 was 85.93%, a 7.48% increase from 2021.
• Blueprint Medicines average gross margin for 2021 was 92.88%, a 7.12% decline from 2020.

Gross margin can be defined as a company's total sales revenue minus its cost of goods sold, divided by the total sales revenue, expressed as a percentage.