• Pfizer average pre-tax profit margin for 2023 was 20.06%, a 38.12% decline from 2022.
• Pfizer average pre-tax profit margin for 2022 was 32.42%, a 21.15% decline from 2021.
• Pfizer average pre-tax profit margin for 2021 was 26.76%, a 67.98% increase from 2020.

Pre-tax profit margin can be defined as earnings before taxes as a portion of total revenue.