• Pfizer average gross margin for 2023 was 64.1%, a 1.01% increase from 2022.
• Pfizer average gross margin for 2022 was 63.46%, a 7.87% increase from 2021.
• Pfizer average gross margin for 2021 was 68.88%, a 14.04% decline from 2020.

Gross margin can be defined as a company's total sales revenue minus its cost of goods sold, divided by the total sales revenue, expressed as a percentage.