• Ionis Pharmaceuticals average return on equity for 2023 was -74.39, a 541.29% increase from 2022.
• Ionis Pharmaceuticals average return on equity for 2022 was -11.6, a 77.24% increase from 2021.
• Ionis Pharmaceuticals average return on equity for 2021 was -50.97, a 2041.6% decline from 2020.

Roe - return on equity can be defined as the amount of net income returned as a percentage of shareholders equity. Return on equity measures a corporation's profitability by revealing how much profit a company generates with the money shareholders have invested.