• Ionis Pharmaceuticals average debt/equity ratio for 2023 was 3.18, a 60.61% increase from 2022.
• Ionis Pharmaceuticals average debt/equity ratio for 2022 was 1.98, a 7.61% increase from 2021.
• Ionis Pharmaceuticals average debt/equity ratio for 2021 was 1.84, a 211.86% increase from 2020.

Debt/equity ratio can be defined as a measure of a company's financial leverage calculated by dividing its long-term debt by stockholders' equity.