Spyre Therapeutics - 9 Year Stock Price History | SYRE

The latest closing stock price for Spyre Therapeutics as of June 20, 2025 is 15.01.

  • An investor who bought $1,000 worth of Spyre Therapeutics stock at the IPO in 2016 would have $-939 today, roughly -1 times their original investment - a -26.65% compound annual growth rate over 9 years.
  • The all-time high Spyre Therapeutics stock closing price was 299.75 on April 08, 2016.
  • The Spyre Therapeutics 52-week high stock price is 40.26, which is 168.2% above the current share price.
  • The Spyre Therapeutics 52-week low stock price is 10.91, which is 27.3% below the current share price.
  • The average Spyre Therapeutics stock price for the last 52 weeks is 23.49.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.

Spyre Therapeutics - 9 Year Stock Price History | SYRE

  • An investor who bought $1,000 worth of Spyre Therapeutics stock at the IPO in 2016 would have $-939 today, roughly -1 times their original investment - a -26.65% compound annual growth rate over 9 years.
  • The all-time high Spyre Therapeutics stock closing price was 299.75 on April 08, 2016.
  • The Spyre Therapeutics 52-week high stock price is 40.26, which is 168.2% above the current share price.
  • The Spyre Therapeutics 52-week low stock price is 10.91, which is 27.3% below the current share price.
  • The average Spyre Therapeutics stock price for the last 52 weeks is 23.49.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.