• Alkermes average gross margin for 2023 was 83.65%, a 2.88% decline from 2022.
• Alkermes average gross margin for 2022 was 81.31%, a 2.59% increase from 2021.
• Alkermes average gross margin for 2021 was 83.47%, a 0.71% decline from 2020.

Gross margin can be defined as a company's total sales revenue minus its cost of goods sold, divided by the total sales revenue, expressed as a percentage.