• Ono Pharmaceutical average gross margin for 2023 was 74.08%, a 0.95% increase from 2022.
• Ono Pharmaceutical average gross margin for 2022 was 73.38%, a 1.05% increase from 2021.
• Ono Pharmaceutical average gross margin for 2021 was 72.62%, a 0.18% increase from 2020.

Gross margin can be defined as a company's total sales revenue minus its cost of goods sold, divided by the total sales revenue, expressed as a percentage.